[Download] "Safety Evaluation of Saffron (Crocus Sativus) Tablets in Healthy Volunteers (Report)" by Phytomedicine: International Journal of Phytotherapy & Phytopharmacology # Book PDF Kindle ePub Free

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eBook details

• Title: Safety Evaluation of Saffron (Crocus Sativus) Tablets in Healthy Volunteers (Report)
• Author : Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
• Release Date : January 01, 2008
• Genre: Life Sciences,Books,Science & Nature,
• Pages : * pages
• Size : 211 KB

Description

Abstract Saffron (Crocus sativus) stigma tablets were evaluated for short-term safety and tolerability in healthy adult volunteers. The study was a double-blind, placebo-controlled design consisting of a 1 week treatment of saffron tablets. Volunteers were divided into 3 groups of 10 each (5 males and 5 females). Group I received placebo; groups 2 and 3 received 200 and 400 mg saffron tablets, respectively, for 7 days. General measures of health were recorded during the study such as hematological, biochemical and electrocardiographic parameters done in pre- and post-treatment periods. Clinical examination showed no gross changes in all volunteers after intervention. Saffron with higher dose (400 mg) decreased standing systolic blood pressure and mean arterial pressures significantly. Saffron decreased slightly some hematological parameters such as red blood cells, hemoglobin, hematocrit and platelets. Saffron increased sodium, blood urea nitrogen and creatinine.

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